Compound class:
Synthetic organic
Comment: Vertilmicin is a semisynthetic aminoglycoside antibacterial that inhibits bacterial growth by inhibiting protein synthesis. It has Gram-negative and Gram-positive activity [1].
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References |
1. Li CR, Yang XY, Lou RH, Zhang WX, Wang YM, Yuan M, Li Y, Chen HZ, Hong B, Sun CH et al.. (2008)
In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. Antimicrob Agents Chemother, 52 (11): 3875-82. [PMID:18710917] |
2. You XF, Li CR, Yang XY, Yuan M, Zhang WX, Lou RH, Wang YM, Li GQ, Chen HZ, Song DQ et al.. (2009)
In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. Antimicrob Agents Chemother, 53 (10): 4525-8. [PMID:19635958] |