Ligand id: 1175

Name: leuprolide

Structure and Physico-chemical Properties

2D Structure
1. Kuphal D, Janovick JA, Kaiser UB, Chin WW, Conn PM. (1994)
Stable transfection of GH3 cells with rat gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid results in expression of a receptor coupled to cyclic adenosine 3',5'-monophosphate-dependent prolactin release via a G-protein.
Endocrinology, 135: 315-320. [PMID:8013367]
2. Struthers RS, Xie Q, Sullivan SK, Reinhart GJ, Kohout TA, Zhu YF, Chen C, Liu XJ, Ling N, Yang W, Maki RA, Bonneville AK, Chen TK, Bozigian HP. (2007)
Pharmacological characterization of a novel nonpeptide antagonist of the human gonadotropin-releasing hormone receptor, NBI-42902.
Endocrinology, 148: 857-867. [PMID:17095587]