2-(3-bromophenyl)histamine

Ligand id: 1194

Name: 2-(3-bromophenyl)histamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 54.7
Molecular weight 265.02
XLogP 2.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL, Leurs R. (2005)
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
J Pharmacol Exp Ther314: 1310-1321. [PMID:15947036]
2. Seifert R, Wenzel-Seifert K, Burckstummer T, Pertz HH, Schunack W, Dove S, Buschauer A, Elz S. (2003)
Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor.
J Pharmacol Exp Ther305: 1104-1115. [PMID:12626648]