Synonyms: Rufol® | sulphamethizole | Thiosulfil®
sulfamethizole is an approved drug (FDA (1953))
Compound class:
Synthetic organic
Comment: Sulfamethizole is an orally available sulfonamide antibacterial compound.
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References |
1. Achari A, Somers DO, Champness JN, Bryant PK, Rosemond J, Stammers DK. (1997)
Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat Struct Biol, 4 (6): 490-7. [PMID:9187658] |
2. Bermingham A, Derrick JP. (2002)
The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery. Bioessays, 24 (7): 637-48. [PMID:12111724] |
3. Goodhope CD. (1954)
Thiosulfil in urinary tract infection. J Urol, 72 (3): 552-6. [PMID:13202246] |
4. Kerrn MB, Klemmensen T, Frimodt-Møller N, Espersen F. (2002)
Susceptibility of Danish Escherichia coli strains isolated from urinary tract infections and bacteraemia, and distribution of sul genes conferring sulphonamide resistance. J Antimicrob Chemother, 50 (4): 513-6. [PMID:12356795] |