Synonyms: ABBV-974 | ABBV974 | GLPG-1837
Compound class:
Synthetic organic
Comment: GLPG1837 is a CFTR potentiator class agent for cystic fibrosis patients with the CFTRG551D variant [1].
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References |
1. Davies JC, Van de Steen O, van Koningsbruggen-Rietschel S, Drevinek P, Derichs N, McKone EF, Kanters D, Allamassey L, Namour F, de Kock H et al.. (2019)
GLPG1837, a CFTR potentiator, in p.Gly551Asp (G551D)-CF patients: An open-label, single-arm, phase 2a study (SAPHIRA1). J Cyst Fibros, 18 (5): 693-699. [PMID:31147302] |