Synonyms: pyrrolidinylmethyltetracycline | Reverin® | SQ 15,659 | Syntetrin® | Velacycline®
rolitetracycline is an approved drug (FDA (1959))
Compound class:
Synthetic organic
Comment: Rolitetracycline is a parenterally delivered prodrug of tetracycline, an antibacterial that has activity against Gram-negative and Gram-positive bacteria.
Note that the structure shown here matches the CAS-assigned structure and is the same as the ChEBI and ChEMBL entries linked to below. There is no exact match in PubChem for the structure shown here. |
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References |
1. Gaillard T, Madamet M, Pradines B. (2015)
Tetracyclines in malaria. Malar J, 14: 445. [PMID:26555664] |
2. Pradines B, Rogier C, Fusai T, Mosnier J, Daries W, Barret E, Parzy D. (2001)
In vitro activities of antibiotics against Plasmodium falciparum are inhibited by iron. Antimicrob Agents Chemother, 45 (6): 1746-50. [PMID:11353621] |
3. SMITH L. (1964)
ROLITETRACYCLINE, AN ANTIBIOTIC FOR PARENTERAL USE. (SYNTETRIN, VELACYCLINE). JAMA, 187: 141. [PMID:14066734] |