Synonyms: NegGram® | Win 18,320
nalidixic acid is an approved drug (FDA (1964), EMA)
Compound class:
Synthetic organic
Comment: Nalidixic acid is a 1,8-naphthyridine derivative belonging to the quinolone class of antibacterial compounds, with activity against Gram-negative bacteria [3].
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References |
1. Andersson MI, MacGowan AP. (2003)
Development of the quinolones. J Antimicrob Chemother, 51 Suppl 1: 1-11. [PMID:12702698] |
2. European Medicines Agency.
Quinolone- and fluoroquinolone-containing medicinal products. Accessed on 16/03/2023. Modified on 16/03/2023. https://www.ema.europa.eu/en/medicines/human/referrals/quinolone-fluoroquinolone-containing-medicinal-products |
3. LESHER GY, FROELICH EJ, GRUETT MD, BAILEY JH, BRUNDAGE RP. (1962)
1,8-NAPHTHYRIDINE DERIVATIVES. A NEW CLASS OF CHEMOTHERAPEUTIC AGENTS. J Med Pharm Chem, 91: 1063-5. [PMID:14056431] |