Compound class:
Synthetic organic
Comment: Hobartine is an alkaloid found in the traditional herbal remedy made from Aristotelia chilensis (maqui) leaves. Inhibition of the activity of periperhal ion channels (such as NaV1.8) may contribute to the analgesic activity of hobartine-containing extracts.
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References |
1. Pérez R, Figueredo C, Burgos V, Cabrera-Pardo JR, Schmidt B, Heydenreich M, Koch A, Deuis JR, Vetter I, Paz C. (2023)
Natural Compounds Purified from the Leaves of Aristotelia chilensis: Makomakinol, a New Alkaloid and the Effect of Aristoteline and Hobartine on NaV Channels. Int J Mol Sci, 24 (21). [PMID:37958488] |