Compound class:
Synthetic organic
Comment: PNU-37883 is a selective antagonist of the vascular form of Kir6 (KATP) channels [1-2]. It is formulated as the hydrochloride salt for experimental use.
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References |
1. Cui Y, Tinker A, Clapp LH. (2003)
Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A. Br J Pharmacol, 139 (1): 122-8. [PMID:12746230] |
2. Kovalev H, Quayle JM, Kamishima T, Lodwick D. (2004)
Molecular analysis of the subtype-selective inhibition of cloned KATP channels by PNU-37883A. Br J Pharmacol, 141 (5): 867-73. [PMID:14757705] |