Ligand Id: 1412
Ligand name [3H]AP4

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 130.66
Molecular weight 183.03
XLogP -4.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands Radio analogues
References
1. Han, G. and Hampson, D. R. (1999)
Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor.
J Biol Chem., 274: 10008-10013. [PMID:10187777]
2. Malherbe, P., Kratzeisen, C., Lundstrom, K., Richards, J. G., Faull, R. L. M. and Mutel, V. (1999)
Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8.
Brain Res. Mol. Brain Res., 67: 201-210. [PMID:10216218]