[3H]AP4

Ligand id: 1412

Name: [3H]AP4    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 130.66
Molecular weight 183.03
XLogP -4.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Han G, Hampson DR. (1999)
Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor.
J Biol Chem.274: 10008-10013. [PMID:10187777]
2. Malherbe P, Kratzeisen C, Lundstrom K, Richards JG, Faull RLM, Mutel V. (1999)
Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8.
Brain Res. Mol. Brain Res.67: 201-210. [PMID:10216218]