Ligand Id: 1444
Ligand name ABT-229

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 125.38
Molecular weight 697.48
XLogP 3.96
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
References
1. Thielemans, L., Depoortere, I., Perret, J., Robberecht, P., Liu, Y., Thijs, T., Carreras, C., Burgeon, E. and Peeters, T. L. (2005)
Desensitization of the human motilin receptor by motilides.
J Pharmacol Exp Ther, 313: 1397-1405. [PMID:15764739]
2. Clark, MJ; Wright, T; Bertrand, PP; Bornstein, JC; Jenkinson, KM; Verlinden, M; Furness, JB. (1999)
Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum.
Clin. Exp. Pharmacol. Physiol., 26 (3): 242-5. [PMID:10081621]