Ligand id: 1445

Name: EM-523

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 165.84
Molecular weight 729.47
XLogP 2.45
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Thielemans L, Depoortere I, Perret J, Robberecht P, Liu Y, Thijs T, Carreras C, Burgeon E, Peeters TL. (2005)
Desensitization of the human motilin receptor by motilides.
J Pharmacol Exp Ther, 313: 1397-1405. [PMID:15764739]