Ligand id: 155

Name: [3H](+)DOB    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 44.48
Molecular weight 273.04
XLogP 2.07
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Lopez-Gimenez JF, Villazon M, Brea J, Loza MI, Palacios JM, Mengod G, Vilaro MT. (2001)
Multiple conformations of native and recombinant human 5-hydroxytryptamine(2a) receptors are labeled by agonists and discriminated by antagonists.
Mol Pharmacol, 60: 690-699. [PMID:11562430]
2. Sleight AJ, Stam NJ, Mutel V, Vanderheyden PM. (1996)
Radiolabelling of the human 5-HT2A receptor with an agonist, a partial agonist and an antagonist: effects on apparent agonist affinities.
Biochem Pharmacol, 51: 71-76. [PMID:8534270]