Ligand Id: 1737
Ligand name Up4dC

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 26
Hydrogen bond donors 10
Rotatable bonds 14
Topological polar surface area 421.51
Molecular weight 774.02
XLogP -8.17
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
References
1. Yerxa, B. R., Sabater, J. R., Davis, C. W., Stutts, M. J., Lang-Furr, M., Picher, M., Jones, A. C., Cowlen, M., Dougherty, R., Boyer, J., Abraham, W. M. and Boucher, R. C. (2002)
Pharmacology of INS37217 [P(1)-(uridine 5')-P(4)- (2'-deoxycytidine 5')tetraphosphate, tetrasodium salt], a next-generation P2Y(2) receptor agonist for the treatment of cystic fibrosis.
J Pharmacol Exp Ther, 302: 871-880. [PMID:12183642]