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Synonyms: human/bovine tuberoinfundibular peptide
Compound class:
Endogenous peptide in human, mouse or rat
Species: Human, Bovine
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Goold CP, Usdin TB, Hoare SR. (2001)
Regions in rat and human parathyroid hormone (PTH) 2 receptors controlling receptor interaction with PTH and with antagonist ligands. J Pharmacol Exp Ther, 299 (2): 678-90. [PMID:11602681] |
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2. Hoare SR, Clark JA, Usdin TB. (2000)
Molecular determinants of tuberoinfundibular peptide of 39 residues (TIP39) selectivity for the parathyroid hormone-2 (PTH2) receptor. N-terminal truncation of TIP39 reverses PTH2 receptor/PTH1 receptor binding selectivity. J Biol Chem, 275 (35): 27274-83. [PMID:10854439] |
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3. Jonsson KB, John MR, Gensure RC, Gardella TJ, Jüppner H. (2001)
Tuberoinfundibular peptide 39 binds to the parathyroid hormone (PTH)/PTH-related peptide receptor, but functions as an antagonist. Endocrinology, 142 (2): 704-9. [PMID:11159842] |
