Ligand id: 1849

Name: ABT-299

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 102.72
Molecular weight 618.15
XLogP 6.47
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Albert DH, Conway RG, Magoc TJ, Tapang P, Rhein DA, Luo G, Holms JH, Davidsen SK, Summers JB, Carter GW. (1999)
Properties of ABT-299, a prodrug of A-85783, a highly potent platelet activating factor receptor antagonist.
J Pharmacol Exp Ther, 277: 1595-1606. [PMID:8667228]