Ligand id: 1850

Name: ABT-491

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 73.02
Molecular weight 479.18
XLogP 4.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Albert DH, Magoc TJ, Tapang P, Luo G, Morgan DW, Curtin M, Sheppard GS, Xu L, Heyman HR, Davidsen SK, Summers JB, Carter GW. (1997)
Pharmacology of ABT-491, a highly potent platelet-activating factor receptor antagonist.
Eur J Pharmacol, 325: 69-80. [PMID:9151941]