Ligand id: 1929

Name: evatanepag

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 105.18
Molecular weight 468.17
XLogP 6.24
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Cameron KO, Lefker BA, Ke HZ, Li M, Zawistoski MP, Tjoa CM, Wright AS, DeNinno SL, Paralkar VM, Owen TA et al.. (2009)
Discovery of CP-533536: an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation.
Bioorg. Med. Chem. Lett., 19 (7): 2075-8. [PMID:19250823]
2. Murase A, Taniguchi Y, Tonai-Kachi H, Nakao K, Takada J. (2008)
In vitro pharmacological characterization of CJ-042794, a novel, potent, and selective prostaglandin EP(4) receptor antagonist.
Life Sci., 82 (3-4): 226-32. [PMID:18155068]