Ligand id: 1955

Name: 13,14-dihydro-16-m-chlorophenoxy-w-tetranor-PGF

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 13
Topological polar surface area 107.22
Molecular weight 428.2
XLogP 3.72
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Wang Y, Wos JA, Dirr MJ, Soper DL, deLong MA, Mieling GE, De B, Amburgey JS, Suchanek EG, Taylor CJ. (2000)
Design and synthesis of 13,14-dihydro prostaglandin F(1alpha) analogues as potent and selective ligands for the human FP receptor.
J Med Chem, 43: 945-952. [PMID:10715159]