AFP-07

Ligand id: 1962

Name: AFP-07

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 86.99
Molecular weight 388.21
XLogP 3.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Chang CS, Negishi M, Nakano T, Morizawa Y, Matsumura Y, Ichikawa A. (1997)
7,7-Difluoroprostacyclin derivative, AFP-07, a highly selective and potent agonist for the prostacyclin receptor.
Prostaglandins53: 83-90. [PMID:9112287]