Ligand id: 2127

Name: senktide

Structure and Physico-chemical Properties

2D Structure
1. Buell G, Schulz MF, Arkinstall SJ, Maury K, Missotten M, Adami N, Talabot F, Kawashima E. (1992)
Molecular characterisation, expression and localisation of human neurokinin-3 receptor.
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Characterization of a neurokinin B receptor site in rat brain using a highly selective radioligand.
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Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist.
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The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity.
J Biol Chem, 271: 20250-20257. [PMID:8702757]
6. Wormser U, Laufer R, Hart Y, Chorev M, Gilon C, Selinger Z. (1986)
Highly selective agonists for substance P receptor subtypes.
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