α-Emtbl

Ligand id: 2363

Name: α-Emtbl

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 42.37
Molecular weight 144.06
XLogP 1.68
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Steinbach JH, Bracamontes J, Yu L, Zhang P, Covey DF. (2000)
Subunit-specific action of an anticonvulsant thiobutyrolactone on recombinant glycine receptors involves a residue in the M2 membrane-spanning region.
Mol. Pharmacol.58 (1): 11-7. [PMID:10860922]