Ligand id: 2461

Name: capsazepine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 87.82
Molecular weight 376.1
XLogP 4.51
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Behrendt HJ, Germann T, Gillen C, Hatt H, Jostock R. (2004)
Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay.
Br. J. Pharmacol., 141 (4): 737-45. [PMID:14757700]
2. McIntyre P, McLatchie LM, Chambers A, Phillips E, Clarke M, Savidge J, Toms C, Peacock M, Shah K, Winter J, Weerasakera N, Webb M, Rang HP, Bevan S, James IF. (2001)
Pharmacological differences between the human and rat vanilloid receptor 1 (VR1).
Br. J. Pharmacol., 132 (5): 1084-94. [PMID:11226139]