Ligand id: 2519

Name: (-)-(R)-efonidipine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 130.05
Molecular weight 631.24
XLogP 8.91
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Furukawa T, Miura R, Honda M, Kamiya N, Mori Y, Takeshita S, Isshiki T, Nukada T. (2004)
Identification of R(-)-isomer of efonidipine as a selective blocker of T-type Ca2+ channels.
Br. J. Pharmacol., 143 (8): 1050-7. [PMID:15545287]