Ligand id: 2629

Name: mexiletine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 35.25
Molecular weight 179.13
XLogP 2.47
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Wang GK, Russell C, Wang SY. (2004)
Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
J. Physiol. (Lond.), 554 (Pt 3): 621-33. [PMID:14608007]