acetyl-podocarpic dimer

Ligand id: 2753

Name: acetyl-podocarpic dimer

Abbreviated name: APD

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Topological polar surface area 95.97
Molecular weight 614.32
XLogP 11.39
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Sparrow CP, Baffic J, Lam MH, Lund EG, Adams AD, Fu X, Hayes N, Jones AB, Macnaul KL, Ondeyka J, Singh S, Wang J, Zhou G, Moller DE, Wright SD, Menke JG. (2002)
A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux.
J. Biol. Chem., 277 (12): 10021-7. [PMID:11790770]