Ligand id: 286

Name: (+)-aceclidine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 30.74
Molecular weight 170.12
XLogP 0.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Ehlert FJ, Griffin MT, Glidden PF. (1996)
The interaction of the enantiomers of aceclidine with subtypes of the muscarinic receptor.
J Pharmacol Exp Ther, 279: 1335-1344. [PMID:8968358]
2. Griffin MT, Figueroa KW, Liller S, Ehlert FJ. (2007)
Estimation of Agonist Activity at G Protein-Coupled Receptors: Analysis of M2 Muscarinic Receptor Signaling through Gi/o,Gs, and G15.
J Pharmacol Exp Ther, 321: 1193-1207. [PMID:17392404]