compound 3h [PMID: 8246234]

Ligand id: 2956

Name: compound 3h [PMID: 8246234]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 71.69
Molecular weight 547.12
XLogP 6.98
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Procopiou PA, Draper CD, Hutson JL, Inglis GG, Ross BC, Watson NS. (1993)
Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors.
J. Med. Chem., 36 (23): 3658-62. [PMID:8246234]