compound 4ff [PMID: 1656041]

Ligand id: 2970

Name: compound 4ff [PMID: 1656041]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 55.76
Molecular weight 400.2
XLogP 6.45
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Jendralla H, Granzer E, von Kerekjarto B, Krause R, Schacht U, Baader E, Bartmann W, Beck G, Bergmann A, Kesseler K. (1991)
Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.
J. Med. Chem.34 (10): 2962-83. [PMID:1656041]