BMY 22089

Ligand id: 2973

Name: BMY 22089

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 90.13
Molecular weight 438.15
XLogP 4.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Sit SY, Parker RA, Motoc I, Han W, Balasubramanian N, Catt JD, Brown PJ, Harte WE, Thompson MD, Wright JJ. (1990)
Synthesis, biological profile, and quantitative structure-activity relationship of a series of novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.
J. Med. Chem., 33 (11): 2982-99. [PMID:2231596]