compound 17 [PMID: 3701793]

Ligand id: 2974

Name: compound 17 [PMID: 3701793]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 46.53
Molecular weight 380.04
XLogP 4.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Stokker GE, Alberts AW, Gilfillan JL, Huff JW, Smith RL. (1986)
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 5. 6-(Fluoren-9-yl)- and 6-(fluoren-9-ylidenyl)-3,5-dihydroxyhexanoic acids and their lactone derivatives.
J. Med. Chem.29 (5): 852-5. [PMID:3701793]