compound 25d [PMID: 19502059]

Ligand id: 2997

Name: compound 25d [PMID: 19502059]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 80.59
Molecular weight 475.23
XLogP 10.84
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Hosoda S, Matsuda D, Tomoda H, Hashimoto M, Aoyama H, Hashimoto Y. (2009)
Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors.
Bioorg. Med. Chem. Lett., 19 (15): 4228-31. [PMID:19502059]