compound 7 [Brinkman et al., 1996]

Ligand id: 3067

Name: compound 7 [Brinkman et al., 1996]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 21.26
Molecular weight 329.18
XLogP 9.67
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Brinkman JA, Damon RE, Fell JB, Perez LB, Scallen TJ, Vedamanda TR. (1996)
Squalene synthase inhibitors: isosteric replacements of the farnesyl chain of benzyl farnesyl amine.
Bioorg. Med. Chem. Lett.6 (21): 2491-2494.