cinnamic acid

Ligand id: 3203

Name: cinnamic acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 37.3
Molecular weight 148.05
XLogP 3.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Ren N, Kaplan R, Hernandez M, Cheng K, Jin L, Taggart AK, Zhu AY, Gan X, Wright SD, Cai TQ. (2009)
Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).
J. Lipid Res., 50 (5): 908-14. [PMID:19136666]
2. Shama Bhat C, Ramasarma T. (1979)
Inhibition of rat liver mevalonate pyrophosphate decarboxylase and mevalonate phosphate kinase by phenyl and phenolic compounds.
Biochem. J., 181 (1): 143-51. [PMID:226078]