apadenoson

Ligand id: 3290

Name: apadenoson

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 4
Rotatable bonds 7
Topological polar surface area 174.71
Molecular weight 486.22
XLogP 1.46
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Jacobson KA, Gao ZG. (2006)
Adenosine receptors as therapeutic targets.
Nat Rev Drug Discov, 5 (3): 247-64. [PMID:16518376]
2. Peirce SM, Skalak TC, Rieger JM, Macdonald TL, Linden J. (2001)
Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation.
Am. J. Physiol. Heart Circ. Physiol., 281 (1): H67-74. [PMID:11406470]