compound B [PMID:18477808]

Ligand id: 3367

Name: compound B [PMID:18477808]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 93.59
Molecular weight 416.02
XLogP 4.32
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Tan CP, Feng Y, Zhou YP, Eiermann GJ, Petrov A, Zhou C, Lin S, Salituro G, Meinke P, Mosley R et al.. (2008)
Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice.
Diabetes, 57 (8): 2211-9. [PMID:18477808]