Ligand id: 3384

Name: ARL66096

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 7
Rotatable bonds 11
Topological polar surface area 324.63
Molecular weight 615.02
XLogP -3.63
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

1. Humphries RG, Tomlinson W, Clegg JA, Ingall AH, Kindon ND, Leff P. (1995)
Pharmacological profile of the novel P2T-purinoceptor antagonist, FPL 67085 in vitro and in the anaesthetized rat in vivo.
Br. J. Pharmacol., 115 (6): 1110-6. [PMID:7582510]
2. Humphries RG, Tomlinson W, Ingall AH, Cage PA, Leff P. (1994)
FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptors.
Br. J. Pharmacol., 113 (3): 1057-63. [PMID:7858849]