Ligand Id: 3637
Ligand name succinic acid

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 74.6
Molecular weight 118.03
XLogP -0.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
References
1. He, W., Miao, F. J., Lin, D. C., Schwandner, R. T., Wang, Z., Gao, J., Chen, J. L., Tian, H. and Ling, L. (2004)
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors.
Nature, 429: 188-193. [PMID:15141213]
2. Högberg, C; Gidlöf, O; Tan, C; Svensson, S; Nilsson-Öhman, J; Erlinge, D; Olde, B. (2011)
Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling.
J. Thromb. Haemost., 9 (2): 361-72. [PMID:21143371]