biphenylindanone A

Ligand id: 3954

Name: biphenylindanone A

Abbreviated name: BINA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 63.6
Molecular weight 454.21
XLogP 8.87
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Bonnefous C, Vernier JM, Hutchinson JH, Gardner MF, Cramer M, James JK, Rowe BA, Daggett LP, Schaffhauser H, Kamenecka TM. (2005)
Biphenyl-indanones: allosteric potentiators of the metabotropic glutamate subtype 2 receptor.
Bioorg. Med. Chem. Lett., 15 (19): 4354-8. [PMID:16046122]