Ligand id: 4039

Name: CP734432

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 108.91
Molecular weight 468.15
XLogP 5.15
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Prasanna G, Fortner J, Xiang C, Zhang E, Carreiro S, Anderson S, Sartnurak S, Wu G, Gukasyan H, Niesman M et al.. (2009)
Ocular pharmacokinetics and hypotensive activity of PF-04475270, an EP4 prostaglandin agonist in preclinical models.
Exp. Eye Res., 89 (5): 608-17. [PMID:19445930]