AMTB

Ligand id: 4132

Name: AMTB

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 83.8
Molecular weight 394.17
XLogP 6.14
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Lashinger ES, Steiginga MS, Hieble JP, Leon LA, Gardner SD, Nagilla R, Davenport EA, Hoffman BE, Laping NJ, Su X. (2008)
AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome.
Am. J. Physiol. Renal Physiol.295 (3): F803-10. [PMID:18562636]