CV-1808

Ligand id: 420

Name: CV-1808

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 5
Rotatable bonds 4
Topological polar surface area 151.57
Molecular weight 358.14
XLogP 0.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Dionisotti S, Ongini E, Zocchi C, Kull B, Arslan G, Fredholm BB. (1997)
Characterization of human A2Aadenosine receptors with the antagonist radioligand [3H]-SCH 58261.
Br. J. Pharmacol.121: 353-360. [PMID:9179373]
2. Kull B, Arslan G, Nilsson C, Owman C, Lorenzen A, Schwabe U, Fredholm BB. (1999)
Differences in the order of potency for agonists, but not antagonists, at human and rat adenosine A2A receptors.
Biochem. Pharmacol.57: 65-75. [PMID:9920286]