Ligand Id: 4213
Ligand name HC067047

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 46.5
Molecular weight 471.21
XLogP 6.82
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
References
1. Everaerts, W; Zhen, X; Ghosh, D; Vriens, J; Gevaert, T; Gilbert, JP; Hayward, NJ; McNamara, CR; Xue, F; Moran, MM; et al.. (2010)
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.
Proc. Natl. Acad. Sci. U.S.A., 107 (44): 19084-9. [PMID:20956320]