CPX

Ligand id: 427

Name: CPX

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 69.3
Molecular weight 236.13
XLogP 1.13
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Ji X, Kim YC, Ahern DG, Linden J, Jacobson KA. (2001)
[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.
Biochem Pharmacol61: 657-663. [PMID:11266650]
2. Kim J, Wess J, van Rhee AM, Schoneberg T, Jacobson KA. (1995)
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
J. Biol. Chem.270: 13987-13997. [PMID:7775460]
3. Linden J, Thai T, Figler H, Jin X, Robeva AS. (1999)
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Mol. Pharmacol.56: 705-713. [PMID:10496952]