canagliflozin

Ligand id: 4582

Name: canagliflozin

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View more information in the IUPHAR Pharmacology Education Project: canagliflozin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 118.39
Molecular weight 444.14
XLogP 5.03
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Liang Y, Arakawa K, Ueta K, Matsushita Y, Kuriyama C, Martin T, Du F, Liu Y, Xu J, Conway B et al.. (2012)
Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models.
PLoS ONE7 (2): e30555. [PMID:22355316]