ataciguat

Ligand id: 5141

Name: ataciguat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 166.88
Molecular weight 574.98
XLogP 3.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Schindler U, Strobel H, Schönafinger K, Linz W, Löhn M, Martorana PA, Rütten H, Schindler PW, Busch AE, Sohn M et al.. (2006)
Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase.
Mol. Pharmacol.69 (4): 1260-8. [PMID:16332991]