EHNA

Ligand id: 5179

Name: EHNA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 91.47
Molecular weight 313.17
XLogP 3.47
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Agarwal RP, Spector T, Parks Jr RE. (1977)
Tight-binding inhibitors--IV. Inhibition of adenosine deaminases by various inhibitors.
Biochem. Pharmacol.26 (5): 359-67. [PMID:849330]
2. Michie AM, Lobban M, Müller T, Harnett MM, Houslay MD. (1996)
Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.
Cell. Signal.8 (2): 97-110. [PMID:8730511]