Synonyms: 1-β-D-galactosphingosine | 1-β-D-galactosylsphingosine | galactosylsphingosine
Compound class:
Metabolite or derivative
Comment: Psychosine is a cytotoxic sphingolipid that accumulates in cell membranes in the absence of functional lysosomal enzyme, galactosylceramidase (GALC) [1].
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References |
1. Hawkins-Salsbury JA, Parameswar AR, Jiang X, Schlesinger PH, Bongarzone E, Ory DS, Demchenko AV, Sands MS. (2013)
Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture. J Lipid Res, 54 (12): 3303-11. [PMID:24006512] |