A-803467

Ligand id: 5734

Name: A-803467

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 60.7
Molecular weight 357.08
XLogP 4.32
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Jarvis MF, Honore P, Shieh CC, Chapman M, Joshi S, Zhang XF, Kort M, Carroll W, Marron B, Atkinson R et al.. (2007)
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
Proc. Natl. Acad. Sci. U.S.A.104 (20): 8520-5. [PMID:17483457]