compound 23 [PMID: 21444206]

Ligand id: 5740

Name: compound 23 [PMID: 21444206]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 139.41
Molecular weight 507.16
XLogP 2.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Semple G, Ren A, Fioravanti B, Pereira G, Calderon I, Choi K, Xiong Y, Shin YJ, Gharbaoui T, Sage CR et al.. (2011)
Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Bioorg. Med. Chem. Lett., 21 (10): 3134-41. [PMID:21444206]